The DREG-56 monoclonal antibody specifically reacts with human CD62L, also known as L-selectin and LECAM-1.
纯化方法
The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
状态
Liquid
浓度
1 mg/mL
缓冲液
Phosphate-buffered aqueous solution, ph7.2.
储存条件
4 °C
储存方法
The product should be stored undiluted at 4°C. Do not freeze.
抗原
L-Selectin (SELL)
(Selectin L (SELL))
别名
CD62L
物质类
Chemical
背景
The DREG-56 monoclonal antibody specifically reacts with human CD62L, also known as L-selectin and LECAM-1. It mediates the migration of lymphocytes to the site of inflammation and their return to the peripheral lymphoid tissues and to the HEV (high endothelial venules). CD62L is expressed on monocytes, NK cells, neutrophils, granulocytes, and subsets of T and B cells. It is reported that the DREG-56 antibody inhibits the binding of lymphocytes to HEV tissue in frozen peripheral tissue.